I had a Dodge p/u with 16" wheels, it originally came with 15" but the previous owner changed them likely wanting to improve mileage. The transmission would shift down at the mere sight of a hill and it was useless towing.
I was amazed one trip, I was in a hurry and cruised the four lane at an indicated 75 (the gears had not been changed). Yeah I was pushing my luck.

I got about 10% better mileage than I did at 60 where the engine was turning 1800 rpm and obviously lugging. I thought the gauge was lying and stopped for gas to make sure it was o.k..